KMID : 0352720180420010016
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Journal of Ginseng Research 2018 Volume.42 No. 1 p.16 ~ p.20
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High-performance liquid chromatography analysis of phytosterols in Panax ginseng root grown under different conditions
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Lee Dong-Gu
Lee Jae-Min Kim Kyung-Tack Lee Sang-Won Kim Young-Ock Cho Ik-Hyun Kim Hak-Jae Park Chun-Gun Lee Sang-Hyun
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Abstract
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Background: The Panax ginseng plant is used as an herbal medicine. Phytosterols of P. ginseng have inhibitory effects on inflammation-related factors in HepG2 cells.
Methods: Phytosterols (e.g., stigmasterol and ¥â-sitosterol) in the roots of P. ginseng grown under various conditions were analyzed using high-performance liquid chromatography. The P. ginseng roots analyzed in this study were collected from three cultivation areas in Korea (i.e., Geumsan, Yeongju, and Jinan) and differed by cultivation year (i.e., 4 years, 5 years, and 6 years) and production process (i.e., straight ginseng, red ginseng, and white ginseng).
Results: The concentrations of stigmasterol and ¥â-sitosterol in P. ginseng roots were 2.22?23.04 mg/g and 7.35?59.09 mg/g, respectively. The highest concentrations of stigmasterol and ¥â-sitosterol were in the roots of 6-year-old P. ginseng cultivated in Jinan (82.14 mg/g and 53.23 mg/g, respectively).
Conclusion: Six-year-old white ginseng and white ginseng cultivated in Jinan containing stigmasterol and ¥â-sitosterol are potentially a new source of income in agriculture.
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KEYWORD
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Panax ginseng, quantitative analysis, root, sterol
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